Single Family Members with Multiple Impacted teeth: A Rare Case Report.

Multiple impacted teeth of idiopathic origin are a rare dental anomaly. Various local and systemic causative factors have been implicated in the literature; however, it is unknown at present about the localization of the genetic defect in the phenotype of failure of eruption. Retained primary teeth is a well-known process, but multiple permanent and supernumerary teeth that too asymptomatic is surely a rare possibility. This article aims in to consolidate and organize the available information regarding the tooth eruption failure and to collaborate the current evidence with the report of three adult sibling’s cases of failure of eruption of multiple permanent teeth in a family without a known cause.

Immunohistochemical study of polycystin-1 in dentigerous cysts.

Background: The alterations involved in step-wise transformation of a dental follicle to dentigerous cyst (DC) is not clearly known. Primary cilium and its protein have been hypothesized to be associated with DC. Mutation of a ciliary protein, polycystin‑1 (PC1) is associated with autosomal dominant polycystic kidney disease. This study was performed to assess the immunohistochemical expression of PC1 between DC and postfunctional follicular tissue (PFFT). Materials and Methods: Thirty‑one consecutive PFFT and 15 DC formed the study group. The PFFT and DC tissues were stained with antibody against PC1. Statistical Package for Social Service was used to analyze data. Descriptive statistics and Student’s Chi‑square test were appropriately used. P ≤0.05 was taken as significant. Results: Fifteen DC (100%) and 7 (22.58%) PFFT were positive for PC1. The difference was statistically significant (P = 0.000). PC1 expression was observed in the cytoplasm with varying intensity. Discussion and Conclusion: All PC1 positive epithelial cells’ cytoplasm stained diffusely. Abnormal cytoplasmic expression of PC1 in all positive epithelial lining indicates that the PC1 probably is associated with cystic transformation.

Tercer molar ectópico impactado en zona retromolar: reporte de caso / Ectopic and impacted third molar in retromolar zone: a case report

El desarrollo dentario resulta de una complicada interacción entre el epitelio oral y el tejido mesenquimático subyacente. La interacción anormal de tejidos en este período podría resultar en el desarrollo y erupción de un diente ectópico. Terceros molares incluidos son una de las patologías más frecuentes encontradas en cirugías oral y maxilofacial. Su evaluación generalmente es radiográfica, y los de ubicación mesioangular son los más prevalentes en la mandíbula. El presente reporte muestra un caso clínico de tercer molar incluido en la región retromolar mandibular. El diagnóstico se efectuó durante una evaluación por medio del análisis de una ortopantomografía en un paciente de sexo femenino de 51 años de edad. La pieza estaba ubicada en la zona retromolar mandibular derecha inmediatamente subcortical. Dado que se encontraba asintomática, sin signos radiográficos ni clínicos de patología, no fue indicada la exodoncia; sin embargo, es importante considerar esta variación anatómica y una posible resolución quirúrgica de ella ante la posible rehabilitación protésica del área.

Tooth develop results of several interactions between oral epithelium end underlying mesenchymatic tissue during odontogenesis. Abnormal relation of tissues could result in develop and eruption of an ectopic tooth. Impacted third molars are a frequent pathology in oral and maxillofacial surgery, it evaluation is commonly radiographic, and the most frequent position in jaw bone is mesioangular. This report wants to show an impacted third molar in mandibular retromolar region. Diagnosis was done through a orthopantomographic study during a clinical evaluation of 51 years of age female patient. Teeth was found sub cortical of right retromolar zone. Considering patient did not related or shown clinical signs of pathology, and radiograph neither had disease compatible signs, was resolved do not proceed to extraction. However, is important to consider this anatomical variation and a possible surgical resolution if a prosthetic rehabilitation of this area.